Cathepsin B Antibody

Catalog Number:

48206

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P07858

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Synthetic peptide (KLH-coupled) within human Cathepsin B C-terminal.

Purification:

Peptide affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC

Background:

Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. In humans, it is coded by the CTSB gene. A wide array of diseases results in elevated levels of cathepsin B, which causes numerous pathological processes including cell death, inflammation, and production of toxic peptides. Focusing on neurological diseases, cathepsin B gene knockout studies in an epileptic rodent model have shown cathepsin B causes a significant amount of the apoptotic cell death that occurs as a result of inducing epilepsy. Mutations in the CTSB gene have been linked to tropical pancreatitis, a form of chronic pancreatitis.

References:

appl_detail:

WB: 1:500-1:1000

ICC: 1:200

Datasheet PDF