Product Datasheet  
Cathepsin B Antibody  
Catalog Number: 48206  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P07858
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide (KLH-coupled) within human Cathepsin B C-terminal.
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:1000

    ICC: 1:200

  • other_names：  
  • Amyloid precursor protein secretase antibody
    APP secretase antibody
    APPS antibody
    CATB_HUMAN antibody
    Cathepsin B heavy chain antibody
    Cathepsin B1 antibody
    CathepsinB antibody
    CPSB antibody
    CTSB ant
  • Purification：  
  • Peptide affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC
  • Background：  
  • Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. In humans, it is coded by the CTSB gene. A wide array of diseases results in elevated levels of cathepsin B, which causes numerous pathological processes including cell death, inflammation, and production of toxic peptides. Focusing on neurological diseases, cathepsin B gene knockout studies in an epileptic rodent model have shown cathepsin B causes a significant amount of the apoptotic cell death that occurs as a result of inducing epilepsy. Mutations in the CTSB gene have been linked to tropical pancreatitis, a form of chronic pancreatitis.



 
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