Bag1 Antibody

Catalog Number:

48176

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q99933

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein within human Bag1 full sequence.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC

Background:

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of alternative translation initiation sites, including a non-AUG site. BAG gene has been implicated in age related neurodegenerative diseases as Alzheimer's. It has been demonstrated that BAG1 and BAG 3 regulate the proteasomal and lysosomal protein elimination pathways, respectively.

References:

appl_detail:

WB: 1:1000

ICC: 1:200

Datasheet PDF