Product Datasheet  
Bag1 Antibody  
Catalog Number: 48176  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q99933
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein within human Bag1 full sequence.
  • reactivity：  
  • Hu,Ms,Rt
  • appl_detail：  
  • WB: 1:1000

    ICC: 1:200

  • other_names：  
  • Bag 1 antibody
    BAG family molecular chaperone regulator 1 antibody
    BAG-1 antibody
    BAG1 antibody
    BAG1_HUMAN antibody
    BCL 2 Associated Athanogene 1 antibody
    BCL 2 associated athanogene antibody
    BCL 2 binding
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC
  • Background：  
  • The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of alternative translation initiation sites, including a non-AUG site. BAG gene has been implicated in age related neurodegenerative diseases as Alzheimer's. It has been demonstrated that BAG1 and BAG 3 regulate the proteasomal and lysosomal protein elimination pathways, respectively.



 
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