Stella Antibody

Catalog Number:	48150
other_names:	Compaction associated protein 1 antibody Developmental pluripotency associated 3 antibody Developmental pluripotency associated protein 3 antibody Developmental pluripotency-associated protein 3 antibody Dppa3 antibody DPPA3_HUMAN
Amount:	100μg
calculated_mw:	17kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:Q6W0C5
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	peptide
Purification:	Immunogen affinity purified
Specificity/Sensitivity:
Applications:	WB, IHC
Background:	Stella is a primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. It participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. It is important for the totipotent/pluripotent states continuing through preimplantation development.
References:
appl_detail:	WB: 1:2,000-1:5,000 IHC: 1:100-1:200
	Datasheet PDF

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