Product Datasheet  
Stella Antibody  
Catalog Number: 48150  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q6W0C5
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu,Ms
  • appl_detail：  
  • WB: 1:2,000-1:5,000
    IHC: 1:100-1:200


  • other_names：  
  • Compaction associated protein 1 antibody
    Developmental pluripotency associated 3 antibody
    Developmental pluripotency associated protein 3 antibody
    Developmental pluripotency-associated protein 3 antibody
    Dppa3 antibody
    DPPA3_HUMAN
  • Purification：  
  • Immunogen affinity purified
  • Specificity：  
  • Applications：  
  • WB, IHC
  • Background：  
  • Stella is a primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. It participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. It is important for the totipotent/pluripotent states continuing through preimplantation development.



 
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