Vang-like protein 1 Antibody

Catalog Number:

48038

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q8TAA9

Form of Antibody:

1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Synthetic peptide within human 100-160 aa.

Purification:

Peptide affinity purified.

Specificity/Sensitivity:

Applications:

WB,ICC

Background:

Vang-like protein 1 is a multi-pass membrane protein, expressed specifically in testis and ovary. It interacts through its C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3. Vangl proteins play a key developmental role in establishing planar cell polarity (PCP) and in regulating convergent extension (CE) movements during embryogenesis. Vangl1 and Vangl2 are both downregulated in several cancer cell lines and primary tumors. Defects in VANGL1 are a cause of neural tube defects (NTD) and a cause of sacral defect with anterior meningocele (SDAM).

References:

appl_detail:

WB: 1:500

ICC: 1:100-1:200

Datasheet PDF