Product Datasheet  
Vang-like protein 1 Antibody  
Catalog Number: 48038  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q8TAA9
  • Form of Antibody：  
  • 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide within human 100-160 aa.
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500

    ICC: 1:100-1:200

  • other_names：  
  • ANGL planar cell polarity protein 1 antibody
    KAI1 C-terminal interacting tetraspanin antibody
    KITENIN antibody
    Loop tail protein 2 homolog antibody
    Loop-tail protein 2 homolog antibody
    LPP2 antibody
    MGC5338 antibo
  • Purification：  
  • Peptide affinity purified.
  • Specificity：  
  • Applications：  
  • WB,ICC
  • Background：  
  • Vang-like protein 1 is a multi-pass membrane protein, expressed specifically in testis and ovary. It interacts through its C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3. Vangl proteins play a key developmental role in establishing planar cell polarity (PCP) and in regulating convergent extension (CE) movements during embryogenesis. Vangl1 and Vangl2 are both downregulated in several cancer cell lines and primary tumors. Defects in VANGL1 are a cause of neural tube defects (NTD) and a cause of sacral defect with anterior meningocele (SDAM).



 
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