Frizzled-5 Antibody

Catalog Number:

48036

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q13467

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

peptide

Purification:

Immunogen affinity purified

Specificity/Sensitivity:

Applications:

WB

Background:

Frizzled-5 belongs to the G-protein coupled receptor Fz/Smo family, contains 585 amino acids. It is localized at the plasma membrane and also found at the Golgi. Fzds have a large extracellular N-terminal region containing a cysteine-rich domain (CRD), which is involved in binding to Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.

References:

appl_detail:

WB: 1:500-1:1000

ICC: 1:100-1:200

Datasheet PDF