Product Datasheet  
Frizzled-5 Antibody  
Catalog Number: 48036  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q13467
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:1000

    ICC: 1:100-1:200

  • other_names：  
  • C2orf31 antibody
    DKFZP434E2135 antibody
    Frizzled 5 seven transmembrane spanning receptor antibody
    Frizzled class receptor 5 antibody
    Frizzled family receptor 5 antibody
    Frizzled homolog 5 antibody
    Frizzled-5 antibody
    Fri
  • Purification：  
  • Immunogen affinity purified
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • Frizzled-5 belongs to the G-protein coupled receptor Fz/Smo family, contains 585 amino acids. It is localized at the plasma membrane and also found at the Golgi. Fzds have a large extracellular N-terminal region containing a cysteine-rich domain (CRD), which is involved in binding to Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.



 
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