1-832-868-1888
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Catalog Number: |
48016 |
| other_names: | B2M antibody B2MG_HUMAN antibody Beta 2 microglobin antibody Beta 2 microglobulin antibody Beta 2 microglobulin precursor antibody Beta chain of mhc class 1 proteins antibody Beta chain of MHC class I molecules antibody |
Amount: |
100μg |
| calculated_mw: | 13kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P61769 |
Form of Antibody: |
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Storage/Stability: |
|
Immunogen: |
peptide |
Purification: |
Immunogen affinity purified |
Specificity/Sensitivity: |
|
Applications: |
WB, IHC, FC |
Background: |
β2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on almost all cells of the body. β-2-Microglobulin associates with the α heavy chain of MHC and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation. |
References: |
|
appl_detail: |
WB: 1:500 |
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