Product Datasheet
Beta-2 Microglobulin Antibody
Catalog Number: 48016
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P61769
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- other_names:
- B2M antibody B2MG_HUMAN antibody Beta 2 microglobin antibody Beta 2 microglobulin antibody Beta 2 microglobulin precursor antibody Beta chain of mhc class 1 proteins antibody Beta chain of MHC class I molecules antibody
- Purification:
- Immunogen affinity purified
- Applications:
- WB, IHC, FC
- Background:
- β2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on almost all cells of the body. β-2-Microglobulin associates with the α heavy chain of MHC and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
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