TIE-1 Antibody

Catalog Number:

47997

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P35590

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Synthetic peptide within human TIE-1 40-120aa.

Purification:

Peptide affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC

Background:

The Tie-1 receptor is an endothelial specific cell surface tyrosine kinase that is indispensable for endothelial functions. Human TIE1 cDNA encodes a 1138 amino acid residue precursor protein with a putative signal peptide, an extracellular domain, and a cytoplasmic domain. Human TIE1/Fc, a disulfide linked homodimeric protein, has a calculated molecular mass of approximately 107 kDa. Tie-1 and Tie-2 are receptor tyrosine kinases (RTKs) that are exclusively expressed in endothelial cells and play important roles in endothelial cell biology.

References:

appl_detail:

WB: 1:1,000-5,000

ICC: 1:50-1:200

Datasheet PDF