Product Datasheet
TIE-1 Antibody
Catalog Number: 47997
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P35590
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic peptide within human TIE-1 40-120aa.
- appl_detail:
- WB: 1:1,000-5,000
ICC: 1:50-1:200
- other_names:
- JKT 14 antibody
JTK14 antibody
TIE antibody
Tie1 antibody
TIE1_HUMAN antibody
Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1 antibody
Tyrosine Kinase with Immunoglobulin and Epi
- Purification:
- Peptide affinity purified
- Background:
- The Tie-1 receptor is an endothelial specific cell surface tyrosine kinase that is indispensable for endothelial functions. Human TIE1 cDNA encodes a 1138 amino acid residue precursor protein with a putative signal peptide, an extracellular domain, and a cytoplasmic domain. Human TIE1/Fc, a disulfide linked homodimeric protein, has a calculated molecular mass of approximately 107 kDa. Tie-1 and Tie-2 are receptor tyrosine kinases (RTKs) that are exclusively expressed in endothelial cells and play important roles in endothelial cell biology.
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