MLKL (Phospho-S345) Antibody

Catalog Number:	13433
other_names:	9130019I15Rik antibody FLJ34389 antibody hMLKL antibody Mixed lineage kinase domain like antibody Mixed lineage kinase domain like protein antibody Mixed lineage kinase domain like pseudokinase antibody Mixed line
Amount:	100μg
calculated_mw:	54 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:Q9D2Y4
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL.
Purification:	ProA affinity purified
Specificity/Sensitivity:
Applications:	IHC
Background:	Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
References:
appl_detail:	IHC: 1:50-1:100
	Datasheet PDF

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