Product Datasheet
MLKL (Phospho-S345) Antibody
Catalog Number: 13433
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9D2Y4
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL.
- appl_detail:
IHC: 1:50-1:100
- other_names:
- 9130019I15Rik antibody
FLJ34389 antibody
hMLKL antibody
Mixed lineage kinase domain like antibody
Mixed lineage kinase domain like protein antibody
Mixed lineage kinase domain like pseudokinase antibody
Mixed line
- Purification:
- ProA affinity purified
- Background:
- Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
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