Product Datasheet  
MLKL (Phospho-S345) Antibody  
Catalog Number: 13433  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q9D2Y4
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL.
  • reactivity:  
  • Ms
  • appl_detail:  

  • IHC: 1:50-1:100


  • other_names:  
  • 9130019I15Rik antibody
    FLJ34389 antibody
    hMLKL antibody
    Mixed lineage kinase domain like antibody
    Mixed lineage kinase domain like protein antibody
    Mixed lineage kinase domain like pseudokinase antibody
    Mixed line
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • IHC
  • Background:  
  • Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.



 
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