GATA3 (Phospho-S308) Antibody

Catalog Number:

13368

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P23771

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Synthetic phospho-peptide corresponding to residues surrounding Ser308 of human GATA3.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, IHC, IP

Background:

GATA-3 antibody (GATA binding protein 3) is a member of the GATA family of transcription factors. GATA-3 appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 has a strong association with estrogen receptor-alpha expression in breast cancer and evidence exists that GATA-3 may be used to predict response to hormonal therapy of breast cancer patients. GATA-3 has also been shown to be a novel marker for bladder cancer. In one study, GATA-3 stained 67% of 308 urothelial carcinomas but no prostate or renal carcinomas.

References:

appl_detail:

WB: 1:1,000-1:2,000
IHC: 1:50-1:200

Datasheet PDF