Product Datasheet
GATA3 (Phospho-S308) Antibody
Catalog Number: 13368
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P23771
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic phospho-peptide corresponding to residues surrounding Ser308 of human GATA3.
- appl_detail:
- WB: 1:1,000-1:2,000
IHC: 1:50-1:200
- other_names:
- GATA 3 antibody
GATA binding factor 3 antibody
GATA binding protein 3 antibody
GATA-binding factor 3 antibody
Gata3 antibody
GATA3_HUMAN antibody
HDR antibody
HDRS antibody
MGC2346 antibody
MG
- Purification:
- ProA affinity purified
- Applications:
- WB, IHC, IP
- Background:
- GATA-3 antibody (GATA binding protein 3) is a member of the GATA family of transcription factors. GATA-3 appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 has a strong association with estrogen receptor-alpha expression in breast cancer and evidence exists that GATA-3 may be used to predict response to hormonal therapy of breast cancer patients. GATA-3 has also been shown to be a novel marker for bladder cancer. In one study, GATA-3 stained 67% of 308 urothelial carcinomas but no prostate or renal carcinomas.
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