OAS2 Polyclonal Antibody

Catalog Number:

49994

Amount:

100μg

Price:

$319

Swiss-Prot No:

Gene ID: 4939
Swiss Prot: P29728

Form of Antibody:

Storage/Stability:

Immunogen:

Synthesized peptide derived from the N-terminal region of human OAS2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

References:

appl_detail:

 WB�?:500 - 1:2000

 IHC�?:100 - 1:300

Datasheet PDF