Product Datasheet  
OAS2 Polyclonal Antibody  
Catalog Number: 49994  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Gene ID: 4939
    Swiss Prot: P29728
  • Form of Antibody：  
  • Storage：  
  • Store at -20°C
  • Immunogen：  
  • Synthesized peptide derived from the N-terminal region of human OAS2.
  • reactivity：  
  • Human
  • appl_detail：  

  •  WB�?:500 - 1:2000

     IHC�?:100 - 1:300

  • other_names：  
  • OAS2; 2'-5'-oligoadenylate synthase 2; (2-5')oligo(A) synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS; p69OAS / p71OAS
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • Applications：  
  • WB,IHC
  • Background：  

  • This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.




 
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