PAIP2 Antibody

Catalog Number:

47790

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9BPZ3
NCBI Gene ID:51247
Gene Accssion:NP_057564

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human PAIP2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PAIP2 protein.

Applications:

WB

Background:

Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.

References:

appl_detail:

WB dilution:1:200-1000

Datasheet PDF