Product Datasheet  
PAIP2 Antibody  
Catalog Number: 47790  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9BPZ3
    NCBI Gene ID:51247
    Gene Accssion:NP_057564
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide of human PAIP2
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB dilution:1:200-1000
  • other_names：  
  • PAIP-2; PAIP2A
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total PAIP2 protein.
  • Applications：  
  • WB
  • Background：  
  • Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.



 
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