IZUMO1R Antibody

Catalog Number:

47763

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:A6ND01
NCBI Gene ID:390243
Gene Accssion:NP_001186135

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human IZUMO1R

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total IZUMO1R protein.

Applications:

IHC

Background:

Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.

References:

appl_detail:

IHC dilution:1: 25-100

Datasheet PDF