Product Datasheet  
IZUMO1R Antibody  
Catalog Number: 47763  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:A6ND01
    NCBI Gene ID:390243
    Gene Accssion:NP_001186135
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide of human IZUMO1R
  • reactivity：  
  • Hu
  • appl_detail：  
  • IHC dilution:1: 25-100
  • other_names：  
  • JUNO; FOLR4; Folbp3
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total IZUMO1R protein.
  • Applications：  
  • IHC
  • Background：  
  • Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.



 
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