VAC14 Antibody

Catalog Number:

47748

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q08AM6
NCBI Gene ID:55697
Gene Accssion:BC007214

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human VAC14

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total VAC14 protein.

Applications:

WB

Background:

This gene encodes a scaffold protein that is a component of the PIKfyve protein kinase complex. This complex is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate, an important component of cellular membranes, from phosphatidylinositol 3-phosphate. Mice lacking a functional copy of this gene exhibit severe neurodegeneration. Mutations in the human gene have been identified in patients with a childhood onset progressive neurological disorder characterized by impaired movement, dystonia, and striatal abnormalities.

References:

appl_detail:

WB dilution:1:200-1000

Datasheet PDF