Product Datasheet  
VAC14 Antibody  
Catalog Number: 47748  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q08AM6
    NCBI Gene ID:55697
    Gene Accssion:BC007214
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein of human VAC14
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  

  • WB dilution:1:200-1000

  • other_names：  
  • TRX; TAX1BP2; ArPIKfyve
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total VAC14 protein.
  • Applications：  
  • WB
  • Background：  

  • This gene encodes a scaffold protein that is a component of the PIKfyve protein kinase complex. This complex is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate, an important component of cellular membranes, from phosphatidylinositol 3-phosphate. Mice lacking a functional copy of this gene exhibit severe neurodegeneration. Mutations in the human gene have been identified in patients with a childhood onset progressive neurological disorder characterized by impaired movement, dystonia, and striatal abnormalities.




 
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