1-832-868-1888
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Catalog Number: |
47720 |
| other_names: | I-MF; I-mfa |
Amount: |
100μg |
| calculated_mw: | 25 kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:Q99750 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein of human MDFI |
Purification: |
Antigen affinity purification |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total MDFI protein. |
Applications: |
WB, IHC |
Background: |
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. |
References: |
|
appl_detail: |
WB dilution:1:500-2000 |
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