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MDFI Antibody

Catalog Number:

47720
other_names: I-MF; I-mfa

Amount:

100μg
calculated_mw: 25 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q99750
NCBI Gene ID:4188
Gene Accssion:BC007836

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human MDFI

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MDFI protein.

Applications:

WB, IHC

Background:

This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

References:

appl_detail:

WB dilution:1:500-2000
IHC dilution:1: 50-300

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