Product Datasheet  
MDFI Antibody  
Catalog Number: 47720  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q99750
    NCBI Gene ID:4188
    Gene Accssion:BC007836
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein of human MDFI
  • reactivity：  
  • Hu, Rt
  • appl_detail：  
  • WB dilution:1:500-2000
    IHC dilution:1: 50-300
  • other_names：  
  • I-MF; I-mfa
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total MDFI protein.
  • Applications：  
  • WB, IHC
  • Background：  
  • This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.



 
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