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ELP1 Antibody

Catalog Number:

47649
other_names: FD; DYS; IKAP; IKI3; TOT1; IKBKAP

Amount:

100μg
calculated_mw: 150 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O95163
NCBI Gene ID:8518
Gene Accssion:NP_003631

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human ELP1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ELP1 protein.

Applications:

WB, IHC

Background:

The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

References:

appl_detail:

WB dilution:1:200-1000
IHC dilution:1: 25-100

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