Product Datasheet  
ELP1 Antibody  
Catalog Number: 47649  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:O95163
    NCBI Gene ID:8518
    Gene Accssion:NP_003631
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide of human ELP1
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB dilution:1:200-1000
    IHC dilution:1: 25-100
  • other_names:  
  • FD; DYS; IKAP; IKI3; TOT1; IKBKAP
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total ELP1 protein.
  • Applications:  
  • WB, IHC
  • Background:  
  • The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.



 
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