Product Datasheet
ELP1 Antibody
Catalog Number: 47649
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O95163
NCBI Gene ID:8518
Gene Accssion:NP_003631
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ELP1
- appl_detail:
- WB dilution:1:200-1000
IHC dilution:1: 25-100
- other_names:
- FD; DYS; IKAP; IKI3; TOT1; IKBKAP
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ELP1 protein.
- Background:
- The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.
© Signalway Biotechnology All Rights Reserved.