HTRA4 Antibody

Catalog Number:

47642

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P83105
NCBI Gene ID:203100
Gene Accssion:NP_710159

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human HTRA4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HTRA4 protein.

Applications:

WB, IHC

Background:

This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.

References:

appl_detail:

WB dilution:1:500-2000
IHC dilution:1: 30-150

Datasheet PDF