Product Datasheet
HTRA4 Antibody
Catalog Number: 47642
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P83105
NCBI Gene ID:203100
Gene Accssion:NP_710159
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human HTRA4
- appl_detail:
- WB dilution:1:500-2000
IHC dilution:1: 30-150
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total HTRA4 protein.
- Background:
- This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
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