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FLNC Antibody

Catalog Number:

47561
other_names: ABPA; ABPL; FLN2; MFM5; MPD4; RCM5; CMH26; ABP-280; ABP280A

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q14315
NCBI Gene ID:2318
Gene Accssion:NP_001449

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human FLNC

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total FLNC protein.

Applications:

IHC

Background:

This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.?

References:

appl_detail:

IHC dilution:1: 30-150

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