Product Datasheet
FLNC Antibody
Catalog Number: 47561
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q14315
NCBI Gene ID:2318
Gene Accssion:NP_001449
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human FLNC
- appl_detail:
- IHC dilution:1: 30-150
- other_names:
- ABPA; ABPL; FLN2; MFM5; MPD4; RCM5; CMH26; ABP-280; ABP280A
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total FLNC protein.
- Background:
- This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.?
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