FBXL4 Antibody

Catalog Number:

47547

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UKA2
NCBI Gene ID:26235
Gene Accssion:NP_036292

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human FBXL4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total FBXL4 protein.

Applications:

WB, IHC

Background:

This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

WB dilution:1:200-1000
IHC dilution:1: 30-150

Datasheet PDF