Product Datasheet
FBXL4 Antibody
Catalog Number: 47547
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UKA2
NCBI Gene ID:26235
Gene Accssion:NP_036292
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human FBXL4
- appl_detail:
- WB dilution:1:200-1000
IHC dilution:1: 30-150
- other_names:
- FBL4; FBL5; MTDPS13
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total FBXL4 protein.
- Background:
- This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants.
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