WNK4 Antibody

Catalog Number:

47499

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q96J92
NCBI Gene ID:65266
Gene Accssion:NP_115763

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human WNK4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total WNK4 protein.

Applications:

IHC

Background:

This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

References:

appl_detail:

IHC dilution:1: 25-100

Datasheet PDF