Product Datasheet
WNK4 Antibody
Catalog Number: 47499
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q96J92
NCBI Gene ID:65266
Gene Accssion:NP_115763
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human WNK4
- appl_detail:
- IHC dilution:1: 25-100
- other_names:
- PHA2B; PRKWNK4
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total WNK4 protein.
- Background:
- This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.
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