Product Datasheet  
WNK4 Antibody  
Catalog Number: 47499  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q96J92
    NCBI Gene ID:65266
    Gene Accssion:NP_115763
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide of human WNK4
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • IHC dilution:1: 25-100
  • other_names:  
  • PHA2B; PRKWNK4
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total WNK4 protein.
  • Applications:  
  • IHC
  • Background:  
  • This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.



 
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