CHD3 Antibody

Catalog Number:

47497

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q12873
NCBI Gene ID:1107
Gene Accssion:NP_001005273

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human CHD3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CHD3 protein.

Applications:

WB, IHC

Background:

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

References:

appl_detail:

WB dilution:1:200-1000
IHC dilution:1: 20-100

Datasheet PDF