Product Datasheet  
CHD3 Antibody  
Catalog Number: 47497  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q12873
    NCBI Gene ID:1107
    Gene Accssion:NP_001005273
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide of human CHD3
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB dilution:1:200-1000
    IHC dilution:1: 20-100
  • other_names：  
  • ZFH; Mi-2a; Mi2-ALPHA
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total CHD3 protein.
  • Applications：  
  • WB, IHC
  • Background：  
  • This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.



 
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