1-832-868-1888
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Catalog Number: |
47464 |
| other_names: | KNTC1AP; hZwilch |
Amount: |
100μg |
| calculated_mw: | 67 kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:Q9H900 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Synthetic peptide of human ZWILCH ? |
Purification: |
Antigen affinity purification |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total ZWILCH ? protein. |
Applications: |
WB |
Background: |
This protein is essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. And it is required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. ZWILCH gene is deleted in a patient suffering from colorectal cancer with chromosomal instability. |
References: |
|
appl_detail: |
WB dilution:1:1000-5000 |
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