Product Datasheet  
ZWILCH Antibody  
Catalog Number: 47464  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9H900
    NCBI Gene ID:55055
    Gene Accssion:NP_060445
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide of human ZWILCH ?
  • reactivity：  
  • Hu, Ms
  • appl_detail：  
  • WB dilution:1:1000-5000
  • other_names：  
  • KNTC1AP; hZwilch
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total ZWILCH ? protein.
  • Applications：  
  • WB
  • Background：  
  • This protein is essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. And it is required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. ZWILCH gene is deleted in a patient suffering from colorectal cancer with chromosomal instability.



 
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