AP1S3 Antibody

Catalog Number:

47427

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q96PC3
NCBI Gene ID:130340
Gene Accssion:BC021898

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human AP1S3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total AP1S3 protein.

Applications:

IHC

Background:

This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants.

References:

appl_detail:

IHC dilution:1: 50-200

Datasheet PDF