Product Datasheet
AP1S3 Antibody
Catalog Number: 47427
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q96PC3
NCBI Gene ID:130340
Gene Accssion:BC021898
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human AP1S3
- appl_detail:
- IHC dilution:1: 50-200
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total AP1S3 protein.
- Background:
- This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants.
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