PPM1B Antibody

Catalog Number:

47357

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O75688
NCBI Gene ID:5495
Gene Accssion:BC012002

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human PPM1B

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PPM1B protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF