Product Datasheet  
PPM1B Antibody  
Catalog Number: 47357  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:O75688
    NCBI Gene ID:5495
    Gene Accssion:BC012002
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein of human PPM1B
  • reactivity：  
  • Hu
  • appl_detail：  
  • IHC dilution:1: 50-300
  • other_names：  
  • PP2CB; PP2CBETA; PP2C-beta; PPC2BETAX; PP2C-beta-X
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total PPM1B protein.
  • Applications：  
  • IHC
  • Background：  
  • The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.



 
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