EXD2 Antibody

Catalog Number:

47304

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9NVH0
NCBI Gene ID:55218
Gene Accssion:BC001962

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human EXD2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total EXD2 protein.

Applications:

WB, IHC

Background:

Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

References:

appl_detail:

WB dilution:1:200-1000
IHC dilution:1: 40-200

Datasheet PDF