Product Datasheet  
EXD2 Antibody  
Catalog Number: 47304  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9NVH0
    NCBI Gene ID:55218
    Gene Accssion:BC001962
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein of human EXD2
  • reactivity：  
  • Hu, Ms
  • appl_detail：  
  • WB dilution:1:200-1000
    IHC dilution:1: 40-200
  • other_names：  
  • EXDL2; C14orf114
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total EXD2 protein.
  • Applications：  
  • WB, IHC
  • Background：  
  • Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.



 
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