UBE2A Antibody

Catalog Number:

47278

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P49459
NCBI Gene ID:7319
Gene Accssion:BC010175

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human UBE2A

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total UBE2A protein.

Applications:

IHC

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.?

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF