Product Datasheet
UBE2A Antibody
Catalog Number: 47278
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P49459
NCBI Gene ID:7319
Gene Accssion:BC010175
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human UBE2A
- appl_detail:
- IHC dilution:1: 50-300
- other_names:
- UBC2; HHR6A; MRXSN; RAD6A; MRXS30
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total UBE2A protein.
- Background:
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.?
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